Preheat the oven to 350°F (175°C).
Cook the egg noodles according to package instructions until al dente, then drain and set aside.
In a large mixing bowl, combine the shredded chicken, cooked egg noodles, frozen mixed vegetables, cream of chicken soup, sour cream, half of the cheddar cheese, garlic powder, onion powder, parsley, salt, and pepper. Mix until well combined.
Transfer the mixture to a greased 9x13-inch baking dish and spread it evenly.
In a small bowl, combine the breadcrumbs with melted butter and the remaining cheddar cheese. Sprinkle this mixture evenly over the top of the noodle bake.
Bake in the preheated oven for 25-30 minutes, or until the top is golden brown and the casserole is heated through.
Let it cool for 5 minutes before serving.